Sumy State University – Medical Institute The history of Sumy State University is begining from 1948, when in the city was founded Amounts training and counseling center of Moscow Institute of the metal industry. In 1993, Sumy Physics and Technology Institute was transformed into Sumy State University – University of…
candidate
Ternopil State Medical University named after Gorbachevsky
Ternopil State Medical University named after Gorbachevsky Ternopil State Medical University Type of educational institution: University Ownership: State Level of accreditation: IV Form of study: Full-time Qualification level: Junior specialist, bachelor, specialist, master Number of students: over 3,200 students , including 1215 foreign nationals from 62 countries. Studying for international students…
V.N.KARAZIN Kharkov National University
V.N KARAZIN Kharkov National University One of the oldest universities in Eastern Europe.The university was found in 1804. Level of accreditation: IV Together with other leading universities in Europe, Karazin University signed the Great Charter of universities in 1988, who founded the Bologna process. Studying…
Vinnitsa National Medical University
Vinnitsa National Medical Universit City: Vinnitsa Year of Foundation: 1921 Title: State Accreditation: IV Document of completion: State Diploma Qualification levels: Master, Bachelor, Specialist The university was founded in 1921. In 1960, the institution was named after NI Pirogov,…
Zaporozhye State Medical University
Zaporozhye State Medical University Modern, multidisciplinary university with the right to autonomous control. Founded in 1903. The university has 615 teachers, including 104 doctors and professors and 417 associate professors and candidates of science. Among university scholars of NAS of Ukraine,…
Digestion and uptake of dietary triacylglycerol
10. Triacylglycerol metabolism 10.2 Digestion and uptake of dietary triacylglycerol Triacylglycerol and its cleavage products Solubilization of fat by detergents Uptake and re-packaging of digested fat in the small intestine The lymphatics drain excess fluid from the interstitial space Chylomicrons are drained from the intestine through…
Compound screening
15. Drug discovery 15.3 Compound screening Peptide deformylase and Met aminopeptidase In vitro screening of Met aminopeptidase inhibitors A non-covalent yet irreversible enzyme inhibitor A generic assay for GPCR activation A cell-based fluorescence assay of membrane depolarization A fluorescence assay of Ca++ influx An in silico docking experiment Electrostatic potential mapped onto the electronic…
Sources of candidate compounds
15. Drug discovery 15.2 Sources of candidate compounds Combinatorial synthesis: the Ugi reaction Semisynthesis of penicillins Semisynthesis of cephalosporins Biosynthesis of polyketides Structure of native 6-deoxyerythronolide B synthase Two compounds produced by engineered variants of 6-deoxyerythronolide B synthase Synthetic libraries Natural compounds Semisynthesis Gene technology Candidate compounds can…